Many people who have gallstones will experience no symptoms. However, if the gallstones are blocking a bile duct, symptoms can occur. People who experience prolonged pain that lasts for more than five hours, nausea and vomiting, fever, chills, yellowish skin or yellow discoloration of the whites of the eyes, or clay-colored stools may be experiencing a gallbladder attack. These attacks can sometimes follow fatty meals or happen at night. Anyone experiencing these symptoms should see a doctor immediately as these can be an indication of a large gallstone or other condition.