Unlike most oral steroids, which are Class II steroids giving most of their anabolic effect by means other than the androgen receptor (AR), it seems that oxandrolone probably does have good binding to the AR, and is thus a class of steroid I, but have little other effect. In itself, it is considered a weakness this is due to its apparent lack of non-AR-mediated activity. This can be corrected by stacking classes with a class II steroids such as Dianabol, Anadrol, 4-AD, or nor-4-AD: the latter two steroids require high blood levels which are not obtained from the use Oral the other part of the reason is that bodybuilders make unfortunate and unreasonable comparisons when judging anabolic steroids. If say 8 tablets per day does little, then the drug is pronounced useless or weak by the user. But it is only 20 mg / day or 140 mg / week. T 140 mg / week testosterone give much results? No. Few anabolic steroids give dramatic results at that dose. Milligram per power is reasonable, but each tablet is weak because the dosage is was introduced on the market in 1964. The purpose of this clinical drug was as a mild alternative to other steroids, so sweet that could even be prescribed to women and children for the purpose of gaining weight following trauma, surgery, severe infection or illness. It has even been prescribed to patients who are unable to maintain a normal weight even without any pathological reason. Currently it has some uses in patients who suffer from myopathy such as oxandrolone steroid users is known as a very potent steroid that is used mainly for cutting purposes. Most people who use oxandrolone will stack it with other cutting steroids like Winstrol and Primobolan Depot. Oxandrolone is often taken in an effort to help maintain muscle mass while losing body does not aromatize or convert to DHT, and has a longer half life than Dianabol - 8 hours against 4 hours. Thus, a moderate dose taken in the morning is largely the system of the night, but provides reasonable levels of androgen during the day and early issues of common shares liver toxicity to 17-alkylated steroids. At one time it was thought that it was not, but clinical and practical experience with oxandrolone has shown that doses of 40 mg / day and higher, liver toxicity is indeed an issue with prolonged use.
Because of its high price, very few bodybuilders have taken large doses of oxandrolone. There is a single case in the medical literature (Forbes et al.) where it is reported that a competitive athlete self-administered 150 mg oxandrolone per day with remarkable gains. This is of uncertain credibility because unless urinalysis was done to verify that no other steroids were taken, there is no way to be certain that the athlete did not actually take more drugs than he reported. In any case, at current prices, only the quite wealthy could afford such a dose. I personally have tried 150 mg/day and considered it somewhat effective, but not dramatically so, and not a preferred regimen.