Oxyethylene glycol

Macrogol 3350, often in combination with electrolytes , is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and anticholinergics . Whole bowel irrigation with macrogol is part of the bowel preparation before surgery or colonoscopy . Limited data also support its use for the treatment of fecal impaction . [7]

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CARBOWAX™ SENTRY™ PEGs and MPEGs are formulated to meet applicable requirements of the National Formulary (NF) and are widely used as excipients for pill and tablet binding or coating, gelatin capsules, ointments and creams, liquid medications, and suppositories. They are also used as active pharmaceutical ingredients (APIs) in such products as laxatives and colonic lavage solutions. They have unique medicament solvent properties, low toxicity, blandness and good water solubility. Polyethylene glycols make excellent water-soluble ointment bases; they spread easily and evenly over the skin even if the skin is moist. Their good water solubility makes it easy to incorporate aqueous ingredients in the formulation, and they do not become rancid or have nutritional value to support microbial growth.

Oxyethylene glycol

oxyethylene glycol

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