Oxymetholone is without a doubt the strongest and most visibly active steroid to date. Not only does it act very rapidly, it causes a virtual explosion of mass. Gains of up to 10 pounds in 2 weeks are not uncommon. This is largely due to a moderate to low androgenic effect combined with a high anabolic activity also mediated by non-AR mechanisms (mechanisms other than simply binding the androgen receptor). You can imagine that the gains made on oxymetholone aren't the leanest. You would note a drastic smoothing out of the muscle due to estrogen-related fat (lipolysis) and water retention. This lipolysis has been shown to be rather drastic. One study1 on long-term hemodialysis patients showed beyond a doubt the role that oxymetholone can play in causing hyperlipedemia. The fat deposition rate, post-hepatic (after processing by the liver), increased drastically in the oxymetholone group while numbers remained stable in the control group.
Oxymetholone should only be used in strict and brief periods. It is the strongest steroid available today, but also one of the most hazardous. Oxymetholone can also cause heptoxicity, which is damaging to the liver. Diarrhea, vomiting, insomnia, stomach pains, headaches and nausea are also side effects associated with Oxymetholone.
Only 1-2, 50 mg tablets of Oxymetholone should be used in a dose. The rule of thumb is to use .5 mg per pound of bodyweight. Oxymetholone should not be used more than two to three weeks at a time and should never be used for more than six weeks.